Dry eye disease (DED) is a chronic, progressive, inflammatory disease of the ocular surface and lacrimal glands. The American Academy of Ophthalmology describes DED as inadequate moisture in the eyes due to changes in tear film consistency and the type of tears produced (leading to evaporative loss), with or without decreased tear production. The disease is also known as keratoconjunctivitis sicca, ocular surface disease, and dry eye syndrome. Nearly 12 million people in the US are coping with dry eye symptoms on a daily basis. The prevalence of DED among adults in the US is approximately 14%. The disease occurs twice as often in women, and increases in prevalence with age (3% at 35 years and nearly 19% at 75 years or older).
Many factors contribute to DED. It has been linked with various autoimmune diseases (eg, Sjogren’s syndrome, lupus, rheumatoid arthritis), diabetes, and thyroid disorders. DED has also been associated with blepharitis and rosacea. In addition, eyelids that are turned in (entropion) or out (ectropion) can result in DED. Postmenopausal women are at high risk for DED – most likely due to hormonal changes resulting in a reduced ophthalmic antiinflammatory response and decreased lacrimal secretions.
Dry eye disease takes its toll on patients economically and on their quality of life. Symptoms range from stinging, irritation, ocular fatigue, to variations in visual acuity. These can occur for extended periods of time and significantly impact a person’s daily activities. In a 2016 report on the humanistic and economic impact of DED in the US, the annual direct cost for managing the disease was estimated at $3.8 billion dollars....
- Pharmacists, Nurse Practitioners, Clinical Nurse Specialists, and Registered Nurses
This CE activity was developed by The Rx Consultant, a publication of Continuing Education Network, Inc.
CE activities for Pharmacists and Pharmacy Technicians:
This continuing education (CE) activity meets the requirements of all state boards of pharmacy for approved continuing education hours. CE credit is automatically reported to CPE Monitor.
CE activities for Nurse Practitioners and Clinical Nurse Specialists:
This continuing education activity meets the requirements of:
The American Nurses Credentialing Center (ANCC) for formally approved continuing education (CE) hours, and CE hours of pharmacotherapeutics.
The American Academy of Nurse Practitioners Certification Program (AANPCP) for acceptable, accredited CE.
This is a pharmacotherapeutics/pharmacology CE activity.
Continuing Education Network, Inc. is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education.
Requirements for CE Credit
- Outline the cause(s) of dry eye disease and identify risk factors associated with its development.
- Be able to recognize dry eye disease symptoms and counsel a patient on self-care measures to improve symptoms.
- Discuss current treatment approaches for dry eye disease including goals of therapy and 4-step management.
- Describe the role of ocular lubricants and antiinflammatory agents in the management of dry eye disease, including their safety and administration. Discuss the role that topical and oral antibiotics may have in DED-related conditions.
Celia P. MacDonnell,, BS Pharmacy, PharmD
Brief Bio : Celia P. MacDonnell, BS Pharmacy, PharmD is a Clinical Professor at the College of Pharmacy, University of Rhode Island. She is also an Adjunct Associate Professor of Family Medicine at the Alpert Medical School at Brown University. Her teaching, practice and research interests are in diseases of the eye and skin, and interprofessional education.